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Cannabis

The cannabis plant is ubiquitous. It might be prohibited in your country; however, you can find many of its products such as hemp seeds – rich in unsaturated fatty acids, proteins and iron, hemp oil and hemp-containing teas on the shelves in nearby stores. The cannabis plant is most known for its natural products THC and CBD but its fibers can be used as textile and even as a building material.

Cannabis sativa L. contains at least 113 phytocannabinoids but the most known is tetrahydrocannabinol (THC), the principal psychoactive compound. The most abundant (40 % of the plant´s extract), cannabidiol (CBD), with possible anti-anxiety and anti-psychotic effects [1], is used as a medication to treat two epileptic disorders [2]. The beneficial effects of THC are acknowledged in the UK and Canada, where a THC-containing medication is prescribed to people with multiple sclerosis to alleviate neuropathic pain, cramps, overactive bladder and other symptoms [3].

A wide variety of THC and CBD beverages have been present in the US market since 2017. As CBD and THC molecules are insoluble in water, they cannot be just added to the water-based drink, packaged and sold. Such a beverage would have an oily layer floating on the top and that would not taste good either. The high-shear homogenization step is required to evenly distribute the oil particles in the beverage, so they are not even noticeable. Dyhydromatics’ ShearJet® processor equipped with the Diamond Reaction Chamber® module applies the high-shear rates to every mL. Each ShearJet model comes with a helicoil heat exchanger that effectively cools your product that exits the Diamond Reaction Chamber, so there is little to no damage to the molecules. This, plus the selection of suitable Reaction Chamber models for each specific application, usually results in fewer passes through the chamber, which speeds up the sample processing, and reduces exposure to temperature fluctuations.

The pharma-grade parts are easy to clean between runs, so you can meet some of the most stringent cGMP sanitation protocols. Also, the portability of the ShearJet HL60 processor makes it an economical addition to your facilities. Just load the processor on a cart and move it to the room where it is needed next.

To learn how easily and effectively you can scale up your beverage production, arrange for a FREE day of testing at +1 978 461 0200. Soon, you will be producing high-quality beverages for years.

Read The Art and Science of Cannabis Powder, a whitepaper written by Le Herbe, which provides an overview of emerging technologies in the cannabis industry that are revolutionizing delivery of bioactive compounds like cannabinoids, terpenoids and flavonoids.

[1] Aizpurua-Olaizola O, Soydaner U, Öztürk E, Schibano D, Simsir Y, Navarro P, et al. "Evolution of the Cannabinoid and Terpene Content during the Growth of Cannabis sativa Plants from Different Chemotypes". Journal of Natural Products, 2016. 79 (2): 324–31. doi:10.1021/acs.jnatprod.5b00949.

[2] Zaheer S, Kumar D, Khan MT, Giyanwani PR, Kiran F. Epilepsy and Cannabis: A Literature Review. Cureus. 2018 Sep 10;10(9):e3278. doi: 10.7759/cureus.3278.

[3] Maniscalco GT, Aponte R, Bruzzese D, Guarcello G, Manzo V, Napolitano M, Moreggia O, Chiariello F, Florio C. THC/CBD oromucosal spray in patients with multiple sclerosis overactive bladder: a pilot prospective study. Neurol Sci. 2018 Jan;39(1):97-102. doi: 10.1007/s10072-017-3148-6.

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