Biotechnology

Nanoemulsions

In whatever way you are using nanoemulsions in your product development, these non-toxic, liquid oil-in-water or water-in-oil emulsions are changing how we get nutrients to plants, distribute coloring to foods, target drug therapies to cancer tumors and so much more.

 

But what is the best equipment for making nanoemulsions? Is there a reliable processor that consistently reduces particles to uniform nano-size and distributes them evenly through the emulsion to improve stability?  Is there an equipment line that will let you seamlessly scale up as demand for your product increases?

 

With Dyhydromatics processors you can take your high-quality nanoemulsion production to the next level and the next and the next.

 

Fabricating nanoemulsions is faster, easier and more reliable with Dyhydromatics ShearJet processors. As the initial macroemulsion flows through the Diamond Reaction Chamber, each mL experiences the same high shear rates This allows you to reliably reproduce uniform, highly stable, precisely-sized nano-droplets. Fewer passes reduce your processing time costs. And the uniformity of the nano-sized particles allows you to sterile-filter your nanoemulsions which can significantly lower your sterilizing expenses, too.

 

Each ShearJet model comes with a simple-feed, jacketed, helicoil heat exchanger. It reduces processing temperatures that can denature or damage your microemulsions so there is less waste of valuable formulations. You will never have to use ice to chill your microemulsion processes again. The pharma-grade parts are easy to clean between runs which helps you meet the most stringent cGMP sanitation protocols. Plus, the portability of the HL60 processor is an economical solution for making multiple batches in multiple compounding rooms daily.

 

To choose the right ShearJet for your nanoemulsion applications, contact us for a FREE day of testing at +1 978 461 0200. You will soon see how easily you can improve your nanoemulsion production for years.

 

 

Cell Disruption

One of the biggest challenges you face is finding equipment that gently ruptures the maximum number of cells so you can harvest the greatest amount of soluble protein and sought-after cell products. Typically, when you increase the rupture rates you also increase processing temperatures and/or pressure levels during cell lysing. These higher temperatures and pressure levels can damage or denature proteins, enzymes, etc., costing you valuable time and wasted product.

 

Now there is a scalable solution for your cell lysing applications.

 

With Dyhydromatics ShearJet processors you can achieve cell rupture rates of 99%-plus and harvest more usable cell material from tough to rupture mammalian, yeast, bacterial (E. coli) and algae cells. As the cells flow through the ShearJet Diamond Reaction Chamber, each experiences the same high shear rates. The resulting large cell membrane fragments make it easier to separate the sought-after cell products from the debris downstream than with a French press, mortar and pestle or high-pressure homogenizers. The ShearJet processing seldom changes the viscosity of the solution, a problem that also occurs when using other cell lysing equipment and techniques.

 

Each Dyhydromatics processor includes a simple feed, helicoil heat exchanger that effectively cools the product in the Diamond Reaction Chamber so there is little to no damage or denaturing of the proteins, etc. You will never need to use ice during the lysing process again. This, plus fewer passes through the chamber, gives you tighter control over the pressure levels, temperature and shearing forces that impact the quality of your harvested cell products.

 

The ShearJet’s pharma-grade parts are easy to clean between runs so you can meet some of the most stringent cGMP sanitation protocols. Also, you will find the portable HL60 processor is an economical solution for disrupting multiple types of cells in multiple rooms throughout the day. Just load the processor on a cart and move it to where it is needed next.

 

To find the right ShearJet for your cell disruption applications, sign up for our FREE day of testing at +1 978 461 0200. Soon, you will be improving your cell disruption and harvesting for years.

 

 

 

Liposomes

Using liposomes for delivery systems is an exciting and expanding area of research and development in biotechnology applications. But one of your biggest challenges is finding ways to scale up your liposome production without using high volumes of expensive solvents in the process. 

 

Dyhydromatics ShearJet processors typically do not require solvents to produce high-quality liposomes. That means you can spend less on solvents (and less time removing them) when you scale up with these high shear processors.

 

At all production levels, the ShearJet’s Diamond Reaction Chamber applies the same high-shear rate to every mL. This allows you to consistently produce high quality, uniform, nano-sized liposomes in the quantities you want. Each ShearJet model comes with a simple feed, helicoil heat exchanger that effectively cools your product in the Diamond Reaction Chamber so there is little-to-no denaturing or damage to your liposomes and therapeutic agents. This, plus fewer passes through the chamber, gives you tighter control over the pressure levels, temperature and shearing forces batch after batch.

 

The ShearJet’s pharma-grade parts are easy to clean between runs which helps you meet some of the most stringent cGMP sanitation protocols. Also, the portability of the HL60 processor makes it an economical addition to your facilities. You simply move it from room to room as you make multiple types of liposomes throughout the day. 

 

To learn how easily and effectively you can scale up your liposome production, arrange for a FREE day of testing at +1 978 461 0200. Soon, you will be producing higher quality liposomes for years.

 
 
 

Kontakt

Zentrale:
Dyhydromatics

63 Great Road, Suite 100, Maynard, MA 01754
 

Telefon +1.978.461.0200 · Fax: +1.978.461.0201
 

Kundenservice: (Option 4)

info@godyhydro.com
Vertrieb: sales@godyhydro.com

Dyhydromatics India:
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Wagle Estate, Thane(W) – 400604, India

 

Phone +91 77381 42553
Email: nrashinkar@godyhydro.com

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Kundenservice Europa:
Telefon +49 7231 1674048 
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