Dyhydromatics Team Achieves Top-10 Finishes at Pforzheim Company Run 2026
June 1, 2026
High-Pressure Homogenizers &
Formulation Solutions
High-Shear Processing for Biotechnology, Pharmaceuticals, Personal Care, Food & Beverage, and Cannabis.
Explore HomogenizersFeaturing the New ShearJet® HL60 V2
(Now Available in 110 VAC)
View HL60 V2
Dyhydromatics designs and manufactures ShearJet® high-pressure homogenizers for advanced high-shear processing applications, supporting customers from formulation development and testing through qualification and scale-up.
Built and tested in Maynard, Massachusetts, ShearJet® systems support uniform nano-sized particle reduction, nanoemulsions, nanosuspensions, liposomes, and cell disruption across pharmaceutical, biotech, food and beverage, personal care, chemical, and cannabis applications.
ShearJet® High-Pressure Homogenizers
Laboratory Through Production-Scale Homogenizer Systems
Small Volume
Compact electric-hydraulic laboratory homogenizer for formulation development, nanoemulsions, liposomes, and high-shear process optimization.
Medium Volume
Pneumatic benchtop homogenizer designed for medium-volume processing, formulation development, and scale-up applications.
R&D & Pilot
Electric-hydraulic homogenizer for process development, pilot processing, increased batch capacity, and extended formulation runs.
Pilot & Production
Electric-hydraulic homogenizer for larger batch sizes, near-continuous flow, process scale-up, and pilot or small-production runs.
Need a complete processing solution? Explore Dyhydromatics Feed & Skid Systems for upstream/downstream process integration, or contact our team to discuss your application, scale-up, and production needs.
Our Services
Proof of Concept Testing
Evaluate formulations and processing feasibility using ShearJet® technology with application-focused testing and detailed performance reporting.
Service & Maintenance
Replacement components, preventative maintenance, and repairs for ShearJet® systems and other high-pressure homogenizer brands.
Formulation Development
With experience in over 1500 formulations over the years, we can address even the most challenging applications to help you determine optimal process parameters for your formulation.
Qualification Support
FAT/SAT, IQ/OQ, validation-ready systems, and documented process control for regulated manufacturing operations.
News, Articles, & Case Studies
Markets that Benefit from Our High Shear Processing.
Pharmaceutical
Consistent uniform particle size reduction (to nano sizes) allows the pharmaceutical industry to create far more stable products with targeted delivery.
Biotechnology
Gentle, productive cell disruption is vital to the biotech industry to study and use the intercellular materials. Demand for these materials is on the increase as they are used in other industries as well, including pharmaceutical, agriculture, and bio-services.
Chemical
Exemplary nanoemulsions, liposomes, and biochemical cell disruption within the chemical industry lead to products with longer shelf-life and stable formulations.
Personal Care / Cosmeceuticals
Nanotechnology allows cosmetics to deliver benefits to a targeted depth, and to eliminate unwanted side affects, like the white coating in sunscreen.
Food / Nutraceuticals
Much advancement has come to fruition in the past decade incorporating nanoemulsions, nanodispersions and encapsulation in the food and beverage industries. These have allowed for targeted delivery of bioactives, longer shelf life, enhanced flavor/aroma, and improved mouth-feel with fat reduction.
Cannabis
While cannabis nanoparticle research is in its infancy, high shear processing is a superior method of increasing bioavailability, and achieving stable formulations.
What They're Saying About Dyhydromatics
Mecozzi Lab Employees
University of Wisconsin-Madison
The best part of working with Dyhydromatics is their customer service. The employees not only have a broad, technical knowledge base but they are also easy to reach over the phone or email and provide unprecedented assistance.
Nelson Landrau
Laundrau Scientific Innovations
I find the ShearJet processor to work more efficiently than the competitive fixed-geometry processor because I can process more material in less time. What took me 3 passes before, I can achieve in one pass on the ShearJet processor.
J. Kendall Killgore
Director, Product Development
Kereos, Inc.
Fortunately for our company, that’s where Dyhydromatics came in. T Field Service Technician did everything – in just a few hours he carried out a complete preventive maintenance on our purchase and then took the time to instruct me on its operation.